Jake Johnson

as Lowery

as Peter B. Parker (voice)

as Peter Parker / Spider-Man (voice) (uncredited)

as Principal Dadier

as Peter B. Parker (voice)

as Barry (voice)

as Chris Vail

as Sebastian Cremmington

as Eli

as Randy 'Chilli' Cilliano

as Ryan Davis

as Oxnard (voice)

as Ronnie

as Jazz Man

as Dave (voice)

as Videographer 2

as Nick Miller

as Jeff

as Grouchy (voice)

as Jesus

as Man on cell phone

as Luke

as Self - Guest

as Powell

as Doc Michael

as Tommy

as Guayabera Shirt Man

as Eddie Garrett

as Basel

as Coach Ben Hopkins (voice)

as Martin

as Self

as Grey McConnell

as Drew

as Tim

as Dustin 'The Hammer' Boyd

as Self - Guest

as Nicholas Jasenovec

as Doug

as Reggie

as Roommate

as William B. Travis

as Lowery (voice)

as Marco Polo

as Karl Hendricks

as Leif

as Peregrine Carruthers

as Daddy

as Self

as Teddy

as Greg

as Self

as Stan (voice)

as Jorgen

as Jake Johnson

as DEA Agent John Haldeman

as Cutler

as Bunny-Hanting Man

as Casting Agent

as Mr. Structor (voice)

as Todd Wells

as Basketball Player

as Self

as Jack

as Steve

as Self

as Self

as Astronaut

as Self

as Peter B. Parker (voice)

as Mr. McKeel (voice)

as Nicholas Jasenovec

as Self

as Barry Sugars

as Self

as Self